IOTA Risk Assessment Models

Ovarian tumor analysis with Voluson™

SIMPLE RULES RISK CALCULATOR

Pre-operative classification system for ovarian tumors

The Simple Rules consist of five features typical for benign tumors (B-features) and five features typical for malignant tumors (M-features). Tumors are classified as Benign, Malignant or Inconclusive:
• Benign: Only B-features apply
• Malignant: Only M-features apply
• Inconclusive: No features apply,
or both B- and M-features apply

Timmerman D, Van Calster B, et al. Am J Obstet Gynecol 2016;214:424-437.

LR2 RISK MODEL

Estimates probability of malignancy

LR2 uses six predictors (one clinical, plus five ultrasound):
• Age
• Maximal diameter of the largest solid component
• Irregular internal cyst walls
• Presence of papillary projections with detectable flow acoustic shadows
• Ascites
The algorithm produces a % of probability.

Timmerman D, et al. J Clin Oncol 2005;23:8794-801.

ADNEX RISK MODEL

Estimates probability a tumor is benign, borderline, stage 1 cancer, stage II-IV cancer or secondary metastatic cancer

The ADNEX model uses nine predictors (three clinical, six ultrasound):

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August 2019
JB69323XX